Anterior Cruciate Ligament (ACL) injuries are common among elite athletes in sports such as football, soccer, and basketball. ACL reconstruction surgery is often necessary to restore knee stability and function. However, recovery can take 6 to 12 months, and reinjury rates remain high. Regenerative medicine, particularly the use of mesenchymal stem cells (MSCs), aims to improve healing of the ligament graft, reduce inflammation, and potentially shorten recovery time.